KPV – 5MG
$48.99
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In Stock
Lyophilized Peptides:
These peptides are freeze-dried, a process that helps support shelf life while preserving the purity and integrity of the peptides during storage.
These peptides are freeze-dried, a process that helps support shelf life while preserving the purity and integrity of the peptides during storage.
COA Documentation:
Every product is supported by batch-specific documentation so researchers can review purity, identity, and quality information before use.
Every product is supported by batch-specific documentation so researchers can review purity, identity, and quality information before use.
99%+ Research-Grade Purity:
Our research peptide products are offered in a 99%+ research-grade purity format and are tested to confirm quality, identity, and consistency.
Our research peptide products are offered in a 99%+ research-grade purity format and are tested to confirm quality, identity, and consistency.
Product Overview
Product Information
Compound: KPV (Lysine–Proline–Valine), a C-terminal tripeptide fragment of α‑MSH.
Form: Lyophilized powder, US-made research-grade, typically ≥98% purity.
Research use only—NOT for human or veterinary application.
COA (Certificate of Analysis)
Batch-tested purity ≥98%. COA available on request—email providers@theratideusa.com.
Research
- Anti‑Inflammatory / Mucosal Healing: In UC mouse models and cell lines, KPV reduces NFκB signaling, accelerates mucosal repair, and lowers TNF‑α expression in colonic epithelial cells :contentReference[oaicite:1]{index=1}.
- PepT1‑mediated Uptake: KPV is transported into intestinal and immune cells via PepT1, enabling its anti‑inflammatory actions :contentReference[oaicite:2]{index=2}.
- Inflammatory Bowel Disease (IBD) Models: Oral KPV (in drinking water) reduced colitis incidence and pro-inflammatory cytokines in DSS and TNBS mouse models :contentReference[oaicite:3]{index=3}.
- Wound Healing & Antimicrobial: Promotes tissue repair, reduces infection, accelerates wound closure, and may support skin health including psoriasis :contentReference[oaicite:4]{index=4}.
- Delivery Advances: HA‑coated nanoparticle formulations enhance targeted delivery to inflamed colon, improving efficacy in ulcerative colitis models :contentReference[oaicite:5]{index=5}.
All findings are from preclinical animal and in vitro studies; no human clinical trials.
FAQ
What is KPV used for?
Research into gut inflammation (e.g., colitis), wound healing, anti-inflammatory, and antimicrobial effects.
How is it administered?
Subject to study—oral, IV, IP, topical, and nanoparticle delivery methods have been reported in preclinical studies.
Is it transportable to tissues?
Yes—pepptide is uptake via PepT1 transporter, accessing intestinal and immune cells :contentReference[oaicite:6]{index=6}.
Side effects?
Preclinical results report no significant toxicity or adverse events in animal studies.
Legal Disclaimer
For research use only—NOT for use in humans, animals, or as dietary supplements.
Safety: Use under laboratory-grade conditions, with appropriate PPE; store at ≤–20 °C.
FDA Notice: These statements have not been evaluated by the FDA. Not intended to diagnose, treat, cure, or
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