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IGF-1 LR3 (1mg)

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Reconstitution Solution 30ML
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Lyophilized Peptides:
These peptides are freeze-dried, a process that helps support shelf life while preserving the purity and integrity of the peptides during storage.
COA Documentation:
Every product is supported by batch-specific documentation so researchers can review purity, identity, and quality information before use.
99%+ Research-Grade Purity:
Our research peptide products are offered in a 99%+ research-grade purity format and are tested to confirm quality, identity, and consistency.

Product Overview

Product Overview

IGF-1 LR3 Overview

IGF-1 LR3 (Insulin-like Growth Factor-1 Long R3) is a synthetic analogue of IGF-1, a naturally occurring growth factor in the human body. IGF-1 is an important mediator of growth hormone (GH) effects, promoting muscle growth, repair, and regeneration. The “Long R3” modification significantly increases its half-life and bioavailability, making it more potent and longer-acting than natural IGF-1.

Peptide Structure

IGF-1 LR3 Structure

Research Applications

In research studies, IGF-1 LR3 has demonstrated potential in:

  • Promoting muscle hypertrophy and preventing atrophy in animal models
  • Enhancing wound healing and tissue repair
  • Improving recovery following nerve injuries
  • Investigating its role in neuroprotection and cognitive function

Due to its extended half-life, IGF-1 LR3 remains active in the body for longer periods, making it a preferred variant for research compared to native IGF-1.

Longevity Research

IGF-1 LR3 is also under investigation for its potential role in longevity and age-related diseases. Research has explored its ability to mitigate sarcopenia (age-related muscle loss), improve bone density, and contribute to overall tissue maintenance and regeneration in aging populations.

Longevity Infographic

Referenced Citations

  1. “Adipose Tissue-Derived Stem Cell Secreted IGF-1 Protects Myoblasts from the Negative Effect of Myostatin.” [Online]. Available: https://www.hindawi.com/journals/bmri/2014/129048/
  2. N. Li, et al., “Myostatin Attenuation In Vivo Reduces Adiposity, but Activates Adipogenesis,” Endocrinology, vol. 157, no. 1, pp. 282–291, Jan. 2016.
  3. E. Corpas, et al., “Human growth hormone and human aging,” Endocr. Rev., vol. 14, no. 1, pp. 20–39, Feb. 1993.
  4. W. E. Sonntag, et al., “Diverse roles of growth hormone and insulin-like growth factor-1 in mammalian aging,” J. Gerontol. A Biol. Sci. Med. Sci., vol. 67, no. 6, pp. 587–598, Jun. 2012.
  5. “IGF-I/IGFBP system: metabolism outline and physical exercise.” [Online]. Available: https://www.ncbi.nlm.nih.gov/pubmed/22714057
  6. B. Y. Hanaoka, et al., “Implications of glucocorticoid therapy in idiopathic inflammatory myopathies,” Nat. Rev. Rheumatol., vol. 8, no. 8, pp. 448–457, Aug. 2012.
  7. A Philippou, et al., J Musculoskelet Neuronal Interact, 2007 [Semantic Scholar]
  8. A Philippou, et al., In vivo, 2009 [Iiar Journals]

All Articles and Product Information Provided On This Website Are For Informational and Educational Purposes Only.

The products offered on this website are furnished for in-vitro studies only. In-vitro studies (Latin: in glass) are performed outside of the body. These products are not medicines or drugs and have not been approved by the FDA to prevent, treat or cure any medical condition, ailment or disease. Bodily introduction of any kind into humans or animals is strictly forbidden by law.

Storage Instructions

All of our products are manufactured using the Lyophilization (Freeze Drying) process, which ensures that our products remain 100% stable for shipping for up to 3-4 months. Once the peptides are reconstituted (mixed with bacteriostatic water), they must be stored in the fridge to maintain stability. After reconstitution, the peptides will remain stable for up to 30 days.

Lyophilization is a unique dehydration process, also known as cryodesiccation, where the peptides are frozen and then subjected to low pressure. This causes the water in the peptide vial to sublimate directly from solid to gas, leaving behind a stable, crystalline white structure known as lyophilized peptide. The puffy white powder can be stored at room temperature until you're ready to reconstitute it with bacteriostatic water.

Once peptides have been received, it is imperative that they are kept cold and away from light. If the peptides will be used immediately, or in the next several days, weeks or months, short-term refrigeration under 4°C (39°F) is generally acceptable. Lyophilized peptides are usually stable at room temperatures for several weeks or more, so if they will be utilized within weeks or months such storage is typically adequate.

However, for longer-term storage (several months to years), it is preferable to store peptides in a freezer at -80°C (-112°F). When storing peptides for months or even years, freezing is optimal to preserve the peptide’s stability.

For further information on proper storage techniques, click the link below:

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All articles and product information provided on this website are for informational and educational purposes only.

The products offered on this website are furnished for in-vitro studies only. In-vitro studies (Latin: in glass) are performed outside of the body. These products are not medicines or drugs and have not been approved by the FDA to prevent, treat, or cure any medical condition, ailment, or disease. Bodily introduction of any kind into humans or animals is strictly forbidden by law.