Product Overview
Compound: Orexin-A (Hypocretin‑1) nasal spray, 5 mg
Format: Powder + nasal atomizer kit (10 mL spray volume)
For research use only—NOT for human or veterinary administration.
Each batch undergoes third-party testing for sequence verification and purity. COAs available upon request—email providers@theratideusa.com.
Intranasal orexin-A bypasses the blood–brain barrier to activate CNS pathways—promising for narcolepsy, sleep deprivation, and cognitive support :contentReference[oaicite:1]{index=1}.
- Narcolepsy (cataplexy): Decreased REM sleep transitions and stabilized sleep architecture in humans :contentReference[oaicite:2]{index=2}.
- Sleep-deprivation reversal: In sleep-deprived monkeys, intranasal orexin-A restored performance on memory tasks better than IV delivery :contentReference[oaicite:3]{index=3}.
- Cognitive enhancement: Improved attention and prefrontal cortical activity in aged rodent and primate models :contentReference[oaicite:4]{index=4}.
- Sympathetic modulation: Nasal orexin-A influences vascular tone, indicating potential autonomic activity :contentReference[oaicite:5]{index=5}.
- Olfactory & REM benefits: In narcolepsy patients, it improved smell sensitivity and reduced REM intrusions :contentReference[oaicite:6]{index=6}.
These findings are based on controlled preclinical and small-scale human studies—further clinical validation is needed.
What can orexin-A nasal spray do?
May enhance wakefulness, cognitive performance, and sleep stability, particularly under deprivation or narcolepsy :contentReference[oaicite:7]{index=7}.
How fast does it work?
In rodents and primates, onset is rapid—with memory task improvements seen minutes after dosing :contentReference[oaicite:8]{index=8}.
Is it safe?
Animal and early human studies report low side effects, though larger clinical trials are needed for full safety profiling.
FDA approved?
No. This product is strictly for research use—no therapeutic claims or FDA approval apply.
This product is sold as a pure compound for laboratory research only—not for human, veterinary, or dietary supplement use. For full terms, please review our Terms & Conditions.
Safety Notice: Handle using appropriate lab protocols. Keep out of reach of unauthorized persons.
FDA Statement: These statements have not been evaluated by the FDA. Not intended to diagnose, treat, cure, or prevent any disease.
