Product Overview
Compound: N‑Acetyl Selank (Ac‑Thr‑Lys‑Pro‑Arg‑Pro‑Gly‑Pro‑Pro; acetylated tuftsin analog)
Form: Lyophilized powder, US-made, research grade ≥98 % purity
For laboratory research only—NOT for human or veterinary use.
Batch-tested ≥98 % purity by HPLC. COA available upon request—email providers@theratideusa.com.
- Anxiolytic & neuroprotective: Comparable to benzodiazepines in anxiolysis without sedation or dependence; downregulates anxiety-related gene expression :contentReference[oaicite:1]{index=1}.
- Gene modulation: Alters expression of key GABAergic, dopaminergic, serotonergic, and ion-channel genes in frontal cortex within 1–3 h post intranasal administration :contentReference[oaicite:2]{index=2}.
- NMDA receptor interaction: Intranasal dosing modulates NMDA glycine-site binding, suggesting enhanced nootropic pathways :contentReference[oaicite:3]{index=3}.
- Enkephalinase inhibition: Acetylated form may extend enkephalin half-life, supporting anxiolytic and neuroprotective effects :contentReference[oaicite:4]{index=4}.
- Enhanced stability: Acetylation improves metabolic stability and duration vs non-acetylated Selank :contentReference[oaicite:5]{index=5}.
Research includes preclinical animal/in vitro and early human trials; no regulatory approval in the U.S.
How does N‑Acetyl Selank work?
Modulates GABAA and NMDA systems, inhibits enkephalinase activity, and affects key neurotransmitter gene expression :contentReference[oaicite:6]{index=6}.
What is it used for in research?
Anxiety relief, neuroprotection, nootropic support, stress modulation, cognitive enhancement.
How is it administered?
Typically via intranasal spray or injection in lab settings; dosing varies per protocol.
Any safety data?
Demonstrates anxiolytic effects without sedative or dependence issues; acetylated form offers improved stability :contentReference[oaicite:7]{index=7}.
For research use only—not for human or veterinary use, nor as a dietary supplement.
Safety: Handle with standard laboratory precautions; store < –20 °C.
FDA Notice: These statements have not been evaluated by the FDA. Not designed to diagnose, treat, cure, or prevent disease.