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VIP – Vasoactive Intestinal Peptide

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3rd party tested peptides

Lyophilized Peptides:
These peptides are freeze-dried, a process that helps support shelf life while preserving the purity and integrity of the peptides during storage.
COA Documentation:
Every product is supported by batch-specific documentation so researchers can review purity, identity, and quality information before use.
99%+ Research-Grade Purity:
Our research peptide products are offered in a 99%+ research-grade purity format and are tested to confirm quality, identity, and consistency.

Product Overview

Compound: Vasoactive Intestinal Peptide (VIP)

Format: Intranasal Spray | 5 mg/mL | 6 mL total

Purity Grades: Lyophilized (99%+ / 98.5%) or non-lyophilized (98.5%)

Origin: USA-made; third-party tested for sequence and purity.

Note: For research use only. Not for human consumption.

Each batch is independently analyzed for identity, purity, and stability. COAs are available upon request—email providers@theratideusa.com.

Vasoactive Intestinal Peptide (VIP) is a natural 28‑amino‑acid neuropeptide originally identified in the gut in the 1970s :contentReference[oaicite:1]{index=1}. It plays a key regulatory role across multiple systems:

  • Gastrointestinal Function: Regulates secretions, smooth‑muscle contractions, blood flow, epithelial barrier integrity, and immune responses during colitis :contentReference[oaicite:2]{index=2}.
  • Neurobiology & Brain Function: Widely expressed in the hippocampus, cortex, and amygdala, involved in learning, memory, affective behavior, synaptic plasticity, and blood‑brain barrier integrity :contentReference[oaicite:3]{index=3}.
  • Immunomodulation & Inflammation: Acts as a potent anti‑inflammatory mediator, shown to reduce pro‑inflammatory cytokines and regulate immune cell activity :contentReference[oaicite:4]{index=4}.
  • Endocrine & Hormonal Regulation: Influences pituitary hormone release, including GH and prolactin :contentReference[oaicite:5]{index=5}.
  • Vascular & Cardiovascular Effects: Causes vasodilation, lowers blood pressure, and affects smooth muscle in multiple systems :contentReference[oaicite:6]{index=6}.

These research findings are based on preclinical models and early human studies.

What is VIP?
VIP is a 28‑amino‑acid neuropeptide and hormone involved in gastrointestinal, nervous, and immune system regulation :contentReference[oaicite:7]{index=7}.

How does it work?
VIP signals through GPCRs (VPAC1/VPAC2), activating cAMP/PKA pathways that modulate smooth muscle, cellular secretion, and gene expression :contentReference[oaicite:8]{index=8}.

What are the potential benefits?
Preclinical research indicates roles in reducing inflammation, supporting cognitive health, maintaining gut integrity, and calming vascular tone. Investigation is ongoing in conditions like colitis, asthma, neurodegeneration, and fibrosis :contentReference[oaicite:9]{index=9}.

Is this for human use?
No. This product is strictly for research/diagnostic use. Not intended for human or veterinary administration.

This product is sold as a pure compound for research purposes only and is not a dietary supplement or intended for human use. Please refer to our Terms & Conditions before ordering.

Safety Information: Keep out of children’s reach. Handle only with appropriate lab equipment. Improper use may cause adverse effects. The product description covers its purity and identity only.

FDA Notice: These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.

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All articles and product information provided on this website are for informational and educational purposes only.

The products offered on this website are furnished for in-vitro studies only. In-vitro studies (Latin: in glass) are performed outside of the body. These products are not medicines or drugs and have not been approved by the FDA to prevent, treat, or cure any medical condition, ailment, or disease. Bodily introduction of any kind into humans or animals is strictly forbidden by law.