Product Overview
Compound: Vasoactive Intestinal Peptide (VIP)
Format: Intranasal Spray | 5 mg/mL | 6 mL total
Purity Grades: Lyophilized (99%+ / 98.5%) or non-lyophilized (98.5%)
Origin: USA-made; third-party tested for sequence and purity.
Note: For research use only. Not for human consumption.
Each batch is independently analyzed for identity, purity, and stability. COAs are available upon request—email providers@theratideusa.com.
Vasoactive Intestinal Peptide (VIP) is a natural 28‑amino‑acid neuropeptide originally identified in the gut in the 1970s :contentReference[oaicite:1]{index=1}. It plays a key regulatory role across multiple systems:
- Gastrointestinal Function: Regulates secretions, smooth‑muscle contractions, blood flow, epithelial barrier integrity, and immune responses during colitis :contentReference[oaicite:2]{index=2}.
- Neurobiology & Brain Function: Widely expressed in the hippocampus, cortex, and amygdala, involved in learning, memory, affective behavior, synaptic plasticity, and blood‑brain barrier integrity :contentReference[oaicite:3]{index=3}.
- Immunomodulation & Inflammation: Acts as a potent anti‑inflammatory mediator, shown to reduce pro‑inflammatory cytokines and regulate immune cell activity :contentReference[oaicite:4]{index=4}.
- Endocrine & Hormonal Regulation: Influences pituitary hormone release, including GH and prolactin :contentReference[oaicite:5]{index=5}.
- Vascular & Cardiovascular Effects: Causes vasodilation, lowers blood pressure, and affects smooth muscle in multiple systems :contentReference[oaicite:6]{index=6}.
These research findings are based on preclinical models and early human studies.
What is VIP?
VIP is a 28‑amino‑acid neuropeptide and hormone involved in gastrointestinal, nervous, and immune system regulation :contentReference[oaicite:7]{index=7}.
How does it work?
VIP signals through GPCRs (VPAC1/VPAC2), activating cAMP/PKA pathways that modulate smooth muscle, cellular secretion, and gene expression :contentReference[oaicite:8]{index=8}.
What are the potential benefits?
Preclinical research indicates roles in reducing inflammation, supporting cognitive health, maintaining gut integrity, and calming vascular tone. Investigation is ongoing in conditions like colitis, asthma, neurodegeneration, and fibrosis :contentReference[oaicite:9]{index=9}.
Is this for human use?
No. This product is strictly for research/diagnostic use. Not intended for human or veterinary administration.
This product is sold as a pure compound for research purposes only and is not a dietary supplement or intended for human use. Please refer to our Terms & Conditions before ordering.
Safety Information: Keep out of children’s reach. Handle only with appropriate lab equipment. Improper use may cause adverse effects. The product description covers its purity and identity only.
FDA Notice: These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.
